Florfenicol is a synthetic broad-spectrum antibiotic effective against most Gram-positive and
Gram-negative bacteria isolated from domestic animals. Florfenicol acts by inhibiting protein
synthesis at the ribosomal level and is bacteriostatic.
Laboratory tests have shown thatflorfenicol is active against the most commonly isolated
bacterial pathogens involved in bovine respiratory disease which include Mannheimia
haemolytica, Pasteurella multocida, Histophilus somni and Arcanobacterium pyogenes, and
against the bacterial pathogens most commonly isolated in respiratory diseases in pigs, including
Actinobacillus pleuropneumoniae and Pasteurella multocida.